Recent research reveals that the use of long-acting insulin will not increase the risk of myocardial infarction (heart attack) in those with type-2 diabetes. The study comes from researchers at the Leibniz Institute for Prevention Research and Epidemiology in Germany.
Researchers examined data from 21,501 individuals with type-2 diabetes. The participants just began using insulin – some used premixed insulin, some analog insulin and some neutral protamine Hagedorn (NPH).
Findings revealed there was no significant increase in the risk of heart attack from any of the three types of long-acting insulin. The findings were published in Diabetes, Obesity and Metabolism.
An alternative study from Japan, however, did find that long-acting insulin could be harmful in patients with type-2 diabetes who also had hypertension. The research was conducted on mice, and it revealed hypertension induces liver cells which are resistant to insulin. This enhances insulin signaling to the heart. This enhanced signaling to the heart increased the mice’s risk of heart failure. It’s imperative that a person with diabetes be weary of insulin if they have hypertension. Additionally, a person with hypertension and diabetes should further work to maintain healthy blood pressure numbers. The findings were published in the Journal of Clinical Investigation.
Role of insulin in blood glucose control
Insulin plays a role in blood glucose control. Due to the glucose produced from the breakdown of food, insulin is released from the pancreas after a meal. Insulin helps muscles, fat and liver cells to absorb glucose which then lowers glucose levels found in the bloodstream. Insulin also stimulates the liver and muscle tissue to store excess glucose – this form of glucose is called glycogen. Lastly, insulin further reduces glucose by reducing the amount produced by the liver.
When a person is healthy glucose and insulin work together to maintain normal levels of each, but in a person with diabetes – where there is too much or too little insulin or the body is resistant to insulin – insulin has to work harder to remove or compensate for the glucose.
Insulin resistance symptoms and causes
Insulin resistance can go undetected for many years (prediabetes) and is often only diagnosed when it has progressed into diabetes. If a person becomes aware of their insulin resistance in the prediabetes stage they can partake in certain habits to reduce their risk or prevent the onset of diabetes.
Causes of insulin resistance include:
- Being overweight
- Lack of exercise
- Steroid use
- Changes in hormones
- Some medications
- Old age
- Ethnicity
- Sleep problems – sleep apnea
- Smoking
Insulin resistance is often symptomless, and a person may have it for many years and not know until it develops into diabetes. Having certain characteristics may offer insight to doctors as to whether or not a person has insulin resistance. Severe insulin resistance does show some symptoms, such as dark patches that appear on the skin around the neck, knees, knuckles and armpits.
How diabetics can maintain heart health
- Manage your diabetes – follow instructions on medications, exercise, lose weight and eat well
- Wear a bracelet or necklace which indicates you are diabetic
- Get your annual physical, including eye exam – diabetes can affect the eyes
- Keep up-to-date on immunizations
- Partake in proper oral hygiene – brush and floss your teeth regularly
- Keep blood pressure and cholesterol in healthy range
- Stop smoking
- Drink alcohol in moderation
- Enjoy foods rich in antioxidants – berries, pomegranates, etc.
Not only will these tips help better improve your diabetes, they can work to protect your heart as well. By taking the necessary steps to better manage diabetes you can reduce your risk of additional health complications – especially ones which may impact your heart.