Three Times Increased Risk of Dementia in Patients with Essential Tremor: Study

Written by Devon Andre
Published on

Study found link between essential tremor and risk of dementiaNew research unveiled today, March 6, 2024, suggests that individuals with essential tremor, a condition causing involuntary shaking, might face a higher risk of dementia compared to the general population. This study will be presented at the American Academy of Neurology’s 76th Annual Meeting from April 13 to April 18, 2024, both in Denver and online.

Essential tremor stands as the most prevalent tremor disorder, surpassing even Parkinson’s disease in frequency. Besides trembling in the arms and hands, those affected might also experience involuntary head, jaw, and voice shaking.

Dr. Elan D. Louis, from the University of Texas Southwestern Medical Center in Dallas and an American Academy of Neurology Fellow, explained that many individuals with essential tremors may only experience mild shaking. He further noted that it could significantly impact some daily activities like writing and eating. He added that their research suggests that along with these tremors, there’s an increased likelihood of developing dementia.

The study observed 222 individuals with essential tremors, averaging 79 years old at the study’s commencement. Cognitive assessments were conducted initially to gauge their cognitive status—whether normal, mildly impaired, or with dementia.

For approximately five years, participants underwent follow-up assessments every 1.5 years. At the study’s onset, 168 individuals had normal cognitive abilities, 35 exhibited mild cognitive impairment, and 19 had dementia.

Throughout the study, 59 participants developed mild cognitive impairment, and 41 developed dementia. By comparing these rates and prevalences to both the general population and individuals with Parkinson’s disease, researchers discovered that the likelihood of developing dementia among participants was three times higher than that of the general population. However, it was lower compared to those with Parkinson’s disease, a group where dementia is more prevalent.

Moreover, during the study period, 27% of participants either had or developed mild cognitive impairment—a rate nearly double that of the general population but less than that observed in individuals with Parkinson’s disease.

Dr. Louis noted that while most individuals with essential tremor won’t develop dementia, their findings underscore the importance for physicians to inform those with essential tremor and their families about the increased risk and potential lifestyle adjustments that may follow this diagnosis.

One limitation of the study was that the comparison data for the general population had been published before the study’s initiation.

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On any matter relating to your health or well-being, please check with an appropriate health professional. No statement herein is to be construed as a diagnosis, treatment, preventative, or cure for any disease, disorder or abnormal physical state. The statements herein have not been evaluated by the Foods and Drugs Administration or Health Canada. Dr. Marchione and the doctors on the Bel Marra Health Editorial Team are compensated by Bel Marra Health for their work in creating content, consulting along with formulating and endorsing products.

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